In most laboratory rodents P. berghei infections cause rapidly fulminating infections leading to death, whereas in the natural host (and several strains of laboratory rats, for example Brown Norway rats) P. berghei causes long lasting, chronic infections with low parasite densities. 1 School of Medicine, Walailak University, Nakhon Si … Groups of mice were exposed intraperitoneally with graded doses of packed red cells or homogenate of spleens of mouse donors infected with a chloro- quine-resistant strain of Plasmodium berghei. Plasmodium berghei: efficacy and safety of combinations of chloroquine and promethazine in chloroquine resistant infections in gravid mice. EXPERIMENTS AND RESULTS Splenic polyribosomal Profiles in the Course ^ of Malaria Infection < In order to correlate the onset of any change in splenic polysomal profiles during the course of Plasmodium berghei infection,^ two groups of Swiss mice were infected in- traperitoneally with 102 and 105 parasitized >" red blood cells, respectively. Eosinophilia was induced by intravenous injection of Ascaris suum body fluid into the mice. Iranian J Parasitol: Vol. Plasmodium berghei infection results into high percent parasitaemia in pregnant mice. Characteristics and cross-resistance patterns of chloroquine-resistant Plasmodium berghei infections in mice. The endothelial cell proliferation and endothelial cytoplasmic changes were greatly stimulated on day 7, at the time when there were collections of dense granular aggregates in the glomerular capillary lumens and electron-dense deposits in the mesangial areas. Antimalarial Activity and Toxicological Assessment of Betula alnoides Extract against Plasmodium berghei Infections in Mice. Prapaporn Chaniad, 1,2 Tachpon Techarang, 1 Arisara Phuwajaroanpong, 1 and Chuchard Punsawad 1,2. Infection of C57BL/6 mice with Plasmodium berghei ANKA induces a fatal neurological disease commonly referred to as experimental cerebral malaria. Nitric oxide decreases cell adhesion molecule expression in the brain during Plasmodium berghei ANKA infection.Expression levels of ICAM-1, VCAM-1, P-selectin and E-selectin in the brain of uninfected and PbA-infected saline-treated and DPTA-NO-treated mice (day 6 of infection). Here we provide clear evidence of liver damage in this model, which precedes and is independent of the onset … In the laboratory the natural hosts have been replaced by a number of commercially available laboratory mouse strains, and the mosquito Anopheles stephensi , which is comparatively easily reared and maintained under defined laboratory conditions. For monitoring the malaria parasitaemia, a Giemsa … The conventional uninfected mice revealed fewer NK cells than the SPF-uninfected mice (5.3 ± 2.9% and 10.2 ± 2.5%, respectively). Renal glomeruli of Plasmodium berghei infected mice were studied electron microscopically. Oduola OO(1), Happi TC, Gbotosho GO, Ogundahunsi OA, Falade CO, Akinboye DO, Sowunmi A, Oduola AM. We demonstrate eradication of PbA infection and prevention of cerebral malaria by artesunate only when given for 14 days. In this study, we investigated the validity of using P. berghei ANKA infection in ICR mice as a model of severe malaria infection. Chloroquine-sensitive rodent malaria parasite, Plasmodium berghei (ANKA strain) was used to infect the Swiss Albino mice in 4-day suppressive and curative models. The catalase activity, an antioxidant decreases during malaria infection. The search for new antimalarial drugs has become an urgent requirement due to resistance to the available drugs and the lack of an effective vaccine. The malaria infection significantly increases the levels of malondialdehyde in pregnant mice. Plasmodium berghei ANKA strain is the parasite of choice because of its ability to sequester within the microcirculation which is the … Therefore, mortality is a consequence of P. berghei infection and not due to 3,15-di-O-acetylbruceolide.